Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by social/communicative difficulties and perseverative behaviours. While research on autism has flourished recently, few studies have been conducted on the disorder in non‐Western contexts. In low‐ and middle‐income countries (LMICs), biomedical research on autism is required to better understand the needs of the population and to develop contextually appropriate interventions. However, autistic individuals are a vulnerable study population and LMICs present with various considerations. While the presentation of autism is heterogeneous, stigma (...) is a common social consequence affecting research. Drawing specifically on the South African context, the ethical intersections of these issues are discussed, along with the limitations of the current informed consent process. Community engagement is recommended as an adjunct to informed consent to ensure that biomedical research is conducted in a more inclusive way. Practical pointers are provided for implementing systematic support for conducting community engagement alongside biomedical research. (shrink)

In The Conditions for Ethical Chemical Restraint, Crutchfield and Redinger (2024) propose ethical standards for the use of chemical restraints, which they consider normatively distinct from physica...

In recent years, campaigns across the globe have called for the removal of objects symbolic of white supremacy. This paper examines the ethics of altering or removing such objects. Do these strategies sanitize history, destroy heritage and suppress freedom of speech? Or are they important steps towards justice? Does removing monuments and renaming schools reflect a lack of parity and unfairly erase local identities? Or can it sometimes be morally required, as an expression of respect for the memories of people (...) who endured past injustices; a recognition of this history's ongoing legacies; and a repudiation of unjust social hierarchies? (shrink)

Unlike gender inequality, racial inequality primarily accumulates across generations. In this article, Dembroff and Payton argue that transracial identification undermines collective reckoning with that injustice.

What should we do with statues and place‐names memorializing people who committed human‐rights abuses linked to slavery and postslavery racism? In this article, I draw on UN principles of transitional justice to address this question. I propose that a successful approach should meet principles of transitional justice recognized by the United Nations, including affirming rights to justice, truth, reparations, and guarantees of nonrecurrence of human rights violations. I discuss four strategies for handling contested heritage, examining strengths and weaknesses of each (...) strategy. Examples from Bristol, England, highlight common challenges and positive lessons. (shrink)

In an influential paper, James Lenman argues that consequentialism can provide no basis for ethical guidance, because we are irredeemably ignorant of most of the consequences of our actions. If our ignorance of distant consequences is great, he says, we can have little reason to recommend one action over another on consequentialist grounds. In this article, I show that for reasons to do with statistical theory, the cluelessness objection is too pessimistic. We have good reason to believe that certain patterns (...) of action will tend to have better consequences, and we have good reason to recommend acting in accordance with strategies based on those advantageous patterns. I close by saying something about the strategies that this argument should lead us to favour. (shrink)

This entry summarizes an emerging subdiscipline of both empirical bioethics and experimental philosophy (“x-phi”) which has variously been referred to as experimental philosophical bioethics, experimental bioethics, or simply “bioxphi”. Like empirical bioethics, bioxphi uses data-driven research methods to capture what various stakeholders think (feel, judge, etc.) about moral issues of relevance to bioethics. However, like its other parent discipline of x-phi, bioxphi tends to favor experiment-based designs drawn from the cognitive sciences – including psychology, neuroscience, and behavioral economics – to (...) tease out why and how stakeholders think as they do. (shrink)

The concept of biodiversity has played a central role within conservation biology over the last thirty years. Precisely how it should be understood, however, is a matter of ongoing debate. In this paper we defend what we call a classic multidimensional conception of biodiversity. We begin by introducing two arguments for eliminating the concept of biodiversity from conservation biology, both of which have been put forward in a recent paper by Santana. The first argument is against the concept’s scientific usefulness. (...) The other is against its value as a target of conservation. We show that neither of these objections is successful against the classic multidimensional conception of biodiversity. Biodiversity thus understood is important from a scientific perspective, because it plays important explanatory roles within contemporary ecology. Moreover, although it does not encompass all valuable features of the natural world, this does not show that we should abandon it as a target of conservation. Instead, biodiversity should be conceived as one of many grounds of value associated with ecosystems. This is consistent with concluding that a central aim of conservationists should be to protect biodiversity. (shrink)

Introduction: A general trend in the psychological literature suggests that guilt contributes to morality more than shame does. Unlike shame-prone individuals, guilt-prone individuals internalize the causality of negative events, attribute responsibility in the first person, and engage in responsible behavior. However, it is not known how guilt- and shame-proneness interact with the attribution of responsibility to others. -/- Methods: In two Web-based experiments, participants reported their attributions of moral culpability (i.e., responsibility, causality, punishment and decision-making) about morally ambiguous acts of (...) killing in different conditions. In Study 1 the vignettes were presented in the 1st person, while in Study 2 in the 3rd person. To test proneness to guilt and shame, we utilized the GASP scale, which differentiates between the affective and behavioral components of each emotion. Statistical analyses were performed in Matlab and R. -/- Results: We found that guilt- and shame-proneness were associated with the severity of attributions in both the first and the third person, but the effect was strong only in the guilt case (both subtypes) and shame-affect case, and not in the shame-behavior case. We call this the Moralizing Effect. -/- Discussion: We wonder whether our finding that guilt-prone people tend to attribute a higher degree of culpability to others is really consistent with the view that guilt motivates people to choose the “moral paths in life”. This echoes views about the harmful aspects of guilt, which have been expressed historically in philosophy, for example, by Friedrich Nietzsche. (shrink)

The paper discusses some of the criticisms of contingent valuation (CV) and allied techniques for estimating the intensity of peoples' preferences for the environment. The weakness of orthodox utilitarian assumptions in economics concerning the commensurability of all items entering into peoples' choices is discussed. The concept of commensurability is explored as is the problem of rational choice between incommensurate alternatives. While the frequent claim that the environment has some unique moral intrinsic value is unsustainable, its preservation often raises ethical and (...) other motivations that are not commensurate with the values that people place on ordinary marketable goods. Nevertheless, CV is also claimed to have some advantages and it is concluded that little progress will be made in this area until both sides in the debate recognise what is valid in their opponents' arguments. (shrink)

This article discusses the ways in which law functions as a determinant of health, historical collaborations between the health and legal professions, the benefits of creating medical-public health-legal collaborations, and how viewing law through a collaborative, population health lens can lead to health equity.

In the first part of my paper I briefly present Jerzy Pelc’s functional approach to logical semiotics of natural language. This approach focuses on the use of natural language expressions and on its dependence on context and conversational situation. One of the important goals of this analysis is to appreciate the role of sentences in natural language and stress that it is by means of sentences that language fulfills its main roles. However, for Pelc almost any expression can be used (...) as a sentence, despite not being a grammatical sentence. In the second part I try to place Pelc’s standpoint within the framework of contemporary semantic minimalism – contextualism debate. I pay special attention to his treatment of subsentential expressions used to express propositions and argue that his view belongs to pragmatics-oriented approaches to subsentential speech acts. (shrink)

W artykule zwracam uwagę na trudności jakie napotyka ktoś, kto chce wcielać w życie postulaty krytycyzmu dotyczące precyzji językowej. Zgodnie z tymi postulatami powinno się mówić jednoznacznie i precyzyjnie, a zatem unikać wyrażeń wieloznacznych, nieostrych i chwiejnych znaczeniowo. Jednakże postulaty te jest znacznie trudniej spełnić niż mogłoby się wydawać, bowiem istotne wątpliwości dotyczą samych zjawisk niejasności, nieostrości czy wieloznaczności. Wydaje się, że chcąc nauczyć innych unikania na przykład wypowiedzi wieloznacznych, powinniśmy dysponować adekwatną charakterystyką wieloznaczności i potrafić ją właściwie diagnozować. Tymczasem, (...) sytuacja jest niesamowicie zagmatwana i w literaturze czy to filozoficznej, czy językoznawczej, nie ma jednej ustalonej definicji, czy choćby zgody co do tego, które wyrażenia są wieloznaczne. Nie ma także zgody co do tego, w jaki sposób charakteryzować polisemię i jak odróżniać ją np. od zależności kontekstowej. Wątpliwości budzi także charakterystyka nieostrości i właściwego klasyfikowania przypadków granicznych wyrażeń nieostrych. Nie ma natomiast wątpliwości, że większość wyrażeń języka naturalnego jest i nieostra, i zależna od kontekstu, i jednocześnie polisemiczna. Co więcej w wielu wypadkach te cechy wcale nie są defektami naszego języka, a wręcz usprawniają komunikację i umożliwiają nam szybkie przekazanie treści. Postulat unikania tego rodzaju wyrażeń jest po prostu nierealizowalny. Kierowanie się zasadami krytycyzmu pozwala jednak na łatwiejsze dostrzeżenie i unikanie wadliwości i uchybień wobec poprawności językowej w tych sytuacjach, gdy takie wadliwości utrudniają sprawną komunikację. (shrink)

The book presents logical foundations of dual tableaux together with a number of their applications both to logics traditionally dealt with in mathematics and philosophy (such as modal, intuitionistic, relevant, and many-valued logics) and to various applied theories of computational logic (such as temporal reasoning, spatial reasoning, fuzzy-set-based reasoning, rough-set-based reasoning, order-of magnitude reasoning, reasoning about programs, threshold logics, logics of conditional decisions). The distinguishing feature of most of these applications is that the corresponding dual tableaux are built in a (...) relational language which provides useful means of presentation of the theories. In this way modularity of dual tableaux is ensured. We do not need to develop and implement each dual tableau from scratch, we should only extend the relational core common to many theories with the rules specific for a particular theory. (shrink)

Drawing on findings from the study of prejudice and prejudice reduction, we identify a number of mechanisms through which religious communities may influence the intergroup attitudes of their members. We hypothesize that religious participation could in principle either reduce or promote prejudice with respect to any given target group. A religious community’s influence on intergroup attitudes will depend upon the specific beliefs, attitudes, and practices found within the community, as well as on interactions between the religious community and the larger (...) social environment in which it is embedded. Basing our proposals on findings from the literature on prejudice formation and prejudice reduction allows us to outline useful directions for future studies of religion and prejudice. (shrink)

The article presents partial results of nationwide research devoted to teaching ethics. It discusses the place of ethics in the Polish education system and the development trends visible since its introduction (1991). When it comes to legislature, acts and ordinances of the Minister of National Education were analyzed. Next to legal acts also judgments of the Constitutional Tribunal, regulating the principles of teaching and assessing the subject of ethics, were discussed. An important aspect of these regulations, due to their practical (...) consequences, is the positioning of ethics as an alternative to the religious education. Statistical data were also analyzed, allowing for a nationwide assessment of the development of interest in the ethics as a subject of school teaching – an increase in the number of schools in which the subject of ethics is taught (depending on the stage of education and the type of school), as well as an increase in the number of full-time equivalent for ethics teachers. The last-mentioned increase, although significant since 2014, is nevertheless small in absolute numbers; ethics still remains a niche subject. Over the years, one can observe an improvement in its status and an increase in social demand. However, the current definition of ethics as an optional subject means that the level of participation still remains low. (shrink)

Journal Name: Semiotica - Journal of the International Association for Semiotic Studies / Revue de l'Association Internationale de Sémiotique Volume: 2013 Issue: 195 Pages: 197-248.

An organization emits carbon dioxide (CO2) and other greenhouse gases (GHGs) through its daily operations, such as the electricity used to power its offices, manufacture products, and then fossil fuels used in vehicles to distribute them. This is referred to as an organization’s carbon footprint, and there is increasing stakeholder and regulatory pressure on management teams globally to reduce them. On other words, it is increasingly critical that the quantity of carbon dioxide and other greenhouse gases that a company is (...) releasing into the atmosphere can be accurately measured in order to ensure that is being reduced accordingly. The European Union Emissions Trading System (EU ETS) is the most crucial tool for decarbonizing Europe, but it has also become a money-making machine. States and financial investors earn; for the power industry, which pays for it, the worst thing is not the system’s presence but its instability. Huge price jumps make it impossible to plan budgets and investments sensibly. This paper provides an introduction to the EU’s Emissions Trading System. As such it provides a discussion of the historical and legal context in which the EU ETS developed and now operates. This article covers the various ways in which these market dynamics, regulatory requirements and stakeholder expectations have converged to make European carbon markets a critical topic for today’s analyst. (shrink)

BackgroundThe pursuit of a cure for HIV is a high priority for researchers, funding agencies, governments and people living with HIV (PLWH). To date, over 250 biomedical studies worldwide are or have been related to discovering a safe, effective, and scalable HIV cure, most of which are early translational research and experimental medicine. As HIV cure research increases, it is critical to identify and address the ethical challenges posed by this research.MethodsWe conducted a scoping review of the growing HIV cure (...) research ethics literature, focusing on articles published in English peer-reviewed journals from 2013 to 2021. We extracted and summarized key developments in the ethics of HIV cure research. Twelve community advocates actively engaged in HIV cure research provided input on this summary and suggested areas warranting further ethical inquiry and foresight via email exchange and video conferencing.DiscussionDespite substantial scholarship related to the ethics of HIV cure research, additional attention should focus on emerging issues in six categories of ethical issues: (1) social value (ongoing and emerging biomedical research and scalability considerations); (2) scientific validity (study design issues, such as the use of analytical treatment interruptions and placebos); (3) fair selection of participants (equity and justice considerations); (4) favorable benefit/risk balance (early phase research, benefit-risk balance, risk perception, psychological risks, and pediatric research); (5) informed consent (attention to language, decision-making, informed consent processes and scientific uncertainty); and (6) respect for enrolled participants and community (perspectives of people living with HIV and affected communities and representation).ConclusionHIV cure research ethics has an unfinished agenda. Scientific research and bioethics should work in tandem to advance ethical HIV cure research. Because the science of HIV cure research will continue to rapidly advance, ethical considerations of the major themes we identified will need to be revisited and refined over time. (shrink)

The livestock sector is under increasing pressure to respond to numerous sustainability and health challenges related to the production and consumption of livestock products. However, political and market barriers and conflicting worldviews and values across the environmental, socio-economic and political domains have led to considerable sector inertia, and government inaction. The processes that lead to the formulation of perspectives in this space, and that shape action (or inaction), are currently under-researched. This paper presents results of a mixed methods exploration of (...) the influence of environmental worldviews, values, and demographic factors on perspectives towards the future of the livestock sector. The approach combines survey and interview data derived from a sample of livestock representatives (N = 307). Respondents with higher pro-environmental, ecocentric and relational worldviews and values favour more behaviour-oriented solutions. Those with lower pro-environmental and higher techno-centric worldviews and values favour technological solutions to improve the efficiency of production and to enable continued patterns of meat consumption. Demographic variation and qualitative data emphasise the need to recognise cultural and geographic nuance in narratives. This study improves our understanding of the processes that lead to the formulation of perspectives, enabling the development of more holistic solutions that acknowledge all voices in an increasingly polarised debate. Adopting more pluralistic, relational methodologies will therefore be paramount in developing solutions for sustainable livestock futures. (shrink)

It is recalled that serious doubts can be raised concerning the status of theories such as those pertaining to the rights of future generations, or the constraints imposed on us by theories of intergenerational justice. At the same time, we do have moral obligations to future generations. But these must be based on an appraisal of what are likely to be the main interests that future generations will have and which of these are most likely to be under permanent threat. (...) These, it is argued, will be in the field of human relations rather than in the field of the environment. It is concluded, therefore, that the most important bequest we can make to future generations is to leave them a society in which there is a greater respect for basic human rights than is the case today throughout most of the world. And since the best way of bequeathing a more decent society to future generations is, of course, to improve the respect for human rights today, there is no conflict of interest between the present generation and future generations. Hence, theories of intergenerational distributive justice are not only untenable but are also unnecessary. (shrink)

This chapter leaves the ‘safe’ world of philosophical speculation and turns to the dangerous world of economic prediction. It outlines the economic reasons for believing that, in the very long term—i.e. abstracting from cyclical or other transitory fluctuations in economic activity—future generations will be incomparably richer than people today. Reasons are also given for believing that there will be no significant obstacles to future growth on account of popularly feared environmental developments, such as running out of ‘finite’ resources, or climate (...) change. (shrink)

Discusses one principle that has been suggested as a guide to the way we ought to take account of the interests of future generations, namely the principle of intergenerational ‘equity’ and its related claim of intergenerational equality, particularly in spheres such as the way we should share out ‘finite’ resources among generations. This chapter examines the possible arguments in favour of intergenerational egalitarianism and concludes that they are difficult to defend. It is proposed that egalitarianism should be replaced by the (...) principle of ‘threshold prioritarianism’, so that our moral obligation to future generations should be based on a humanitarian concern to avoid policies that may impoverish them. (shrink)

During the last two or three decades, various developments in the environmental sphere have led to increasing concern with our obligations to posterity and to the non‐human part of the natural world. These developments have exposed gaps in both traditional, moral, and political theory and in conventional economics. Environmental issues have exposed these gaps and have brought to the fore questions such as how far the society, with whose welfare we are concerned, includes future generations or is limited to individual (...) nations or human beings. This book examines these questions as well as related ethical aspects of environmental policy, such as environmental valuation or the equitable allocation among nations of the burden of environmental protection. (shrink)

Some current environmental problems are global and have public good elements that raise, in an acute form, the question of how the costs of a collective effort from which the world as a whole will benefit should be shared out among poor and rich countries. This chapter discusses how far theories of justice provide guidance to this question. It argues that the answer seems to be ‘very little’ and that, in order to arrive at some ground rules for allocating the (...) burden of global environmental protection between countries—as between generations—we are forced back on humanitarian principles of concern for the poor. (shrink)

It is argued that although there may be some case, on economic grounds, for international cooperative action to deal with the threat of climate change or an excessive depletion of biodiversity, the advantages of participation in such action are probably not very great for most rich countries. Furthermore, some of the ‘ethical’ arguments advanced in support of the view that the rich countries should shoulder most of the burden of international action are weak. Nevertheless, there is a case for the (...) richer countries to do so both on grounds of a moral responsibility to assist very poor people and on grounds of the need to look at international cooperation in a wider framework that takes account of the dependence of cooperation from different groups of countries in dealing with a host of other international problems. (shrink)

Although there are many theories of justice, one crucial feature of those that are most widely accepted is that they lay down principles that determine the allocation of rights and obligations in society. They do not eliminate conflicts of interest between different groups but, by specifying such principles, they are designed to enable conflicting interests to be resolved in a peaceful and harmonious manner. But insofar as future generations cannot be said to have any rights, their interests cannot be protected (...) within the framework of any theory of intergenerational justice. This chapter discusses the general relationship between ‘rights’ and ‘justice’, and the obstacles to any theory of intergenerational justice. (shrink)

Even if future generations have no rights and intergenerational justice, intergenerational egalitarianism, and sustainable development are all flawed, this does relieve us of a moral obligation to take account of the impact of our policies on the interests of future generations. In this chapter we argue that whereas, in the very long run, it seems that widespread acute poverty will be eliminated and a decent environment will be preserved, there seems to be no prospect of ever eradicating the inherent weaknesses (...) of the human psyche that are responsible for some groups in society imposing intolerable suffering on others. Hence, it seems that the most valuable bequest we could make to future generations would be a more decent, tolerant, and ‘just’ society than the one in which most people live today. Furthermore, there is clear evidence that the greatest environmental damage has been done in countries where there has been the least respect for basic human rights. (shrink)

This chapter discusses critically the main criticisms of the use of cost‐benefit analysis in environmental policy, such as the incommensurability of environmental values with the values born by marketable goods, and the related unreliability of estimates of peoples’ willingness to pay for environmental protection. While it is found that there is some strength in these criticisms, it is still necessary to take account of the resource constraint involved in decisions concerning public goods. Furthermore, a democratic society needs some impartial and (...) transparent process for solving allocation problems. However, the need to reconcile the valid objections made by environmentalists to cost‐benefit analysis with the problems raised by resource constraints raises new problems of political theory and institutions. (shrink)

Another widely suggested principle governing our obligations to future generations is ‘sustainable development’. The first part of this chapter argues that the mainstream interpretations of the concept of sustainable development are open to serious objections on ethical grounds. The chapter also shows that even if intergenerational egalitarianism were a viable objective there is nothing intergenerationally egalitarian about sustainable development.

Generations are not homogeneous entities and are composed of individuals and nations that have conflicting interests in the way in which resources are allocated among competing uses. This chapter discusses whether ‘the environment’, or ‘nature’, should enjoy special status in any allocation; whether the economist's approach is too anthropocentric; the concept of ‘intrinsic’ values; and the application of these concepts to environmental valuation. It is argued that while many environmental assets are ‘public goods’, so that the free market is unlikely (...) to supply the socially optimal amount, the same applies to many other things, such as public health or education services or the arts, not to mention the fact that most people in the world are, anyway, in dire need of a simple increase in their ability to buy simple basic private goods. This means that the allocation of resources to environmental objectives ought to take into account some form of cost‐benefit analysis. (shrink)

It is widely believed that environmental conservation has to be guided by respect for the ‘rights’ of future generations. But it is argued in this chapter that it may not be plausible to think in terms of the ‘rights’ of future generations in general or their rights to any specific environmental assets. Future generations may well have rights when they come into existence, but these will only be rights that can be satisfied at the time. But ‘rights’ do not exhaust (...) the whole of morality, and future generations will certainly have interests, which means that we are under moral obligation to take account of them and of the effect that our environmental policies may have on them. Thus, the problem is to predict what the main interests of future generations will be and how to weigh them up against the interests of people alive today. It is argued that this approach will lead to a very different ranking of priorities among our moral obligations to future generations. (shrink)

Electrotherapy is a dynamically developing method of treatment of sinus node dysfunction and atrioventricular conduction disturbances. It is an extremely important method used in the treatment of heart failure. The aim of this paper was to use classification trees for the differentiation between patients implanted with one of the three electrotherapy devices, i.e. SC-VVI/aai, DC-DDD, ICD/crt. The analysed data concerned 2071 patients who underwent implantation or device replacement procedures in the years 2010–2018, hospitalized in a coronary care unit. CART-type classification (...) trees with 5-fold cross-validation were used for the analysis. The decision concerning the choice of a particular electrotherapy device is always made based on the latest guidelines and the patient’s clinical condition. The used classification trees may enable verification of the state of implementation of guidelines in real-life therapeutic decisions. (shrink)

This paper presents the benefits they can obtain business which aim to protect the environment. The environment protection has found its place and affects the process of systemic change of the Polish economy. This article assumes that building a competitive economy and enterprise development based on the principle of sustainable development requires the development of mechanisms for mutual benefits. These will be the economic mechanisms, technical and technological, and social. All these mechanisms are concentrated in clusters. Pursue sustainable development policies, (...) an emphasis on environmental protection will be the general element for them a competitive advantage. Sustainable development will in this case be both the agent and the goal of economic and entrepreneurship development. Basing on the assumption that economic development is possible through the achievement of competitive advantage, sustainable development should be treated as its source. (shrink)

This article investigates the new phenomenon of e-mailed questions to a radio phone-in programme, BBC Radio 4's `Election Call'. Our interest in this phenomenon arose for several reasons. First, as a new form, e-mails were singled out at the beginning of each broadcast for special instructions to listeners, although there was evidence that as the series progressed, dealing with e-mail became more of a routine event in each subsequent programme. Second, on listening to the Election Call broadcasts, the sequential introduction (...) of an e-mail question appeared to be problematic for the host. First mentions of e-mailed questions were often subject to a noticeable amount of disfluency and repair work, in contrast to the well-rehearsed and highly routine introduction of callers' questions. Third, we are interested in the function of e-mail questions in terms of how they are handled by the host and guest. Are they given the same status as a `call', and if not, where do the differences lie? In our analysis we show how the introduction of this new media form into a well-established context opens up new structural possibilities for both host as interviewer and politician as interviewee, in terms of how questions get framed, and how they get responded to. (shrink)

BackgroundHIV cure research involving cell and gene therapy has intensified in recent years. There is a growing need to identify ethical standards and safeguards to ensure cell and gene therapy (CGT) HIV cure research remains valued and acceptable to as many stakeholders as possible as it advances on a global scale.MethodsTo elicit preliminary ethical and practical considerations to guide CGT HIV cure research, we implemented a qualitative, in-depth interview study with three key stakeholder groups in the United States: (1) biomedical (...) HIV cure researchers, (2) bioethicists, and (3) community stakeholders. Interviews permitted evaluation of informants’ perspectives on how CGT HIV cure research should ethically occur, and were transcribed verbatim. We applied conventional content analysis focused on inductive reasoning to analyze the rich qualitative data and derive key ethical and practical considerations related to CGT towards an HIV cure.ResultsWe interviewed 13 biomedical researchers, 5 community members, and 1 bioethicist. Informants generated considerations related to: perceived benefits of CGT towards an HIV cure, perceived risks, considerations necessary to ensure an acceptable benefit/risk balance, CGT strategies considered unacceptable, additional ethical considerations, and considerations for first-in-human CGT HIV cure trials. Informants also proposed important safeguards to developing CGT approaches towards an HIV cure, such as the importance of mitigating off-target effects, mitigating risks associated with long-term duration of CGT interventions, and mitigating risks of immune overreactions.ConclusionOur study identified preliminary considerations for CGT-based HIV cure across three key stakeholder groups. Respondents identified an ideal cure strategy as one which would durably control HIV infection, protect the individual from re-acquisition, and eliminate transmission to others. Known and unknown risks should be anticipated and perceived as learning opportunities to preserve and honor the altruism of participants. Preclinical studies should support these considerations and be transparently reviewed by regulatory experts and peers prior to first-in-human studies. To protect the public trust in CGT HIV cure research, ethical and practical considerations should be periodically revisited and updated as the science continues to evolve. Additional ethics studies are required to expand stakeholder participation to include traditionally marginalized groups and clinical care providers. (shrink)

Journal of Philosophy of Education, Volume 55, Issue 6, Page 935-948, December 2021.

How can philosophy expand to be a discipline via which young people from diverse backgrounds feel they can make a direct and positive contribution to their communities? In this chapter I suggest some creative methods by which philosophers can support community-led change. Collaborators and I have been developing the approaches described here through work on issues of racial justice, but they can be applied to campaigns or public debate on any topic. Developing more community-led, socially engaged methods has the potential (...) to make philosophy a more attractive discipline for young people from diverse backgrounds who are keen to use their skills to make a positive difference to their communities. (shrink)

Gregory Bateson said that we are “governed by epistemologies that we know to be wrong” back in 1972. In the same book Bateson wrote: “the organism that destroys its environment destroys itself.” Almost forty years later, global ecological systems are in steep decline and converging crises make a deep evaluation of the underlying premises of our philosophical traditions an urgent imperative. This paper will suggest that the roots of the economic crisis are epistemological and that, to correct this error, whole (...) systems thinking and ecological literacy will become increasingly important in business management as well as in other disciplines. It will also suggest that the economic crisis opened new political space and has provided an opportunity for intervention. If we are brave enough to examine the roots of our problems there is possibility for renewal. (shrink)

The main focus of the paper is the role of listeners’ emotion-relevant characteristics and musical expertise in the granularity of affective responses to music. Another objective of the study is to test the consistency of the granularity of affect that is perceived in music and/or experienced in response to it. In Experiment 1, 91 musicians and nonmusicians listened to musical excerpts and grouped them according to the similarity of the affects they experienced while listening. Finer grouping granularity was found in (...) musicians and high rumination scorers. Male musicians with above-median scores in rumination produced a larger number of clusters than the other male participants. Experiment 2 that engaged 23 participants demonstrated moderate consistency with which listeners grouped affects that they perceived in music and affects they experienced while listening to music. The study suggests that affective responses to music are subject to individual differences in musical expertise and rumination. Affects perceived in music and felt in response to it seem to be categorized with reference to the common principles. However, the cues that are used in such instances of categorization seem to be different. The paper encourages further research on the importance of listeners’ personal characteristics for the affective responses to music. (shrink)